There have been talks about a possible new Blade movie since quite a long time. Director Stephen Norrington and Scriptwriter David Goyer were even thinking about doing a prequel that would focus on the character of Deacon Frost (played by Stephen Dorff in the first film) instead of Blade (Wesley Snipes)...
But fans are still hoping that Blade 4 would star Wesley Snipe as the lead character. Well, seems like this could happen since Wesley Snipes said he would be interested in doing it:
He confirmed again his interest in doing Blade 4 during an interview with MTV:
There are some things we really want to do that we didn't get a chance to do. The first and the second one were experiments, and we started to get better. If we do another one, it will reflect our maturity and our better understanding of the genre
[I'd like to see] a larger, multiracial cast, and it would be great to have some rehearsals before some of the action sequences."
Well let's hope the studios will Wesley Snipes and that the movie Blade 4 will be greenlit soon!